| 1 | |  Club Olimpia | 22 | 15 | 4 | 3 | 42 | 19 | 23 | 49 | B01:00 | 13/11/22 | R 22  Club Olimpia 1 Nacional Asuncion 1 G01:30 | 09/11/22 | R 21 Sol De America 0 Club Olimpia 2 G01:30 | 31/10/22 | R 20 Club Olimpia 3 12 De Octubre De Itaugua 1 G16:00 | 27/10/22 | R 19 Resistencia FC 1 Club Olimpia 6 G01:30 | 23/10/22 | R 18 Club Olimpia 2 Club General Caballero Jlm 1 G22:00 | 16/10/22 | R 17 Cerro Porteno 1 Club Olimpia 2 |
| 2 | |  Cerro Porteno | 22 | 14 | 6 | 2 | 32 | 13 | 19 | 48 | G01:00 | 13/11/22 | R 22 Guairena FC 1 Cerro Porteno 3 G01:30 | 08/11/22 | R 21 Cerro Porteno 1 Resistencia FC 0 B02:00 | 01/11/22 | R 20 Libertad Asuncion 0 Cerro Porteno 0 G02:00 | 28/10/22 | R 19 Cerro Porteno 2 Club General Caballero Jlm 1 G23:00 | 23/10/22 | R 18 Club Guarani 1 Cerro Porteno 2 M22:00 | 16/10/22 | R 17 Cerro Porteno 1 Club Olimpia 2 |
| 3 | |  Nacional Asuncion | 22 | 13 | 6 | 3 | 30 | 16 | 14 | 45 | B01:00 | 13/11/22 | R 22 Club Olimpia 1 Nacional Asuncion 1 M01:30 | 09/11/22 | R 21 Nacional Asuncion 0 Sportivo Ameliano 2 M23:30 | 31/10/22 | R 20 Tacuary Asuncion 2 Nacional Asuncion 1 G23:00 | 27/10/22 | R 19 Nacional Asuncion 3 Guairena FC 0 G01:30 | 24/10/22 | R 18 Libertad Asuncion 0 Nacional Asuncion 1 G02:00 | 17/10/22 | R 17 Nacional Asuncion 2 Club Guarani 0 |
| 4 | |  Libertad Asuncion | 22 | 10 | 4 | 8 | 35 | 27 | 8 | 34 | M01:00 | 13/11/22 | R 22 Tacuary Asuncion 1 Libertad Asuncion 0 G23:00 | 06/11/22 | R 21 Libertad Asuncion 4 Guairena FC 2 B02:00 | 01/11/22 | R 20 Libertad Asuncion 0 Cerro Porteno 0 G23:00 | 27/10/22 | R 19 Club Guarani 1 Libertad Asuncion 2 M01:30 | 24/10/22 | R 18 Libertad Asuncion 0 Nacional Asuncion 1 B01:00 | 18/10/22 | R 17 Sol De America 1 Libertad Asuncion 1 |
| 5 | |  Tacuary Asuncion | 22 | 9 | 4 | 9 | 27 | 25 | 2 | 31 | G01:00 | 13/11/22 | R 22 Tacuary Asuncion 1 Libertad Asuncion 0 M01:30 | 07/11/22 | R 21 Club Guarani 2 Tacuary Asuncion 1 G23:30 | 31/10/22 | R 20 Tacuary Asuncion 2 Nacional Asuncion 1 B01:00 | 26/10/22 | R 19 Sol De America 2 Tacuary Asuncion 2 G01:30 | 22/10/22 | R 18 Tacuary Asuncion 5 12 De Octubre De Itaugua 1 G23:00 | 15/10/22 | R 17 Resistencia FC 0 Tacuary Asuncion 3 |
| 6 | |  Club General Caballero Jlm | 21 | 8 | 3 | 10 | 26 | 26 | 0 | 27 | G01:30 | 09/11/22 | R 21 12 De Octubre De Itaugua 0 Club General Caballero Jlm 3 G23:30 | 01/11/22 | R 20 Club General Caballero Jlm 1 Resistencia FC 0 M02:00 | 28/10/22 | R 19 Cerro Porteno 2 Club General Caballero Jlm 1 M01:30 | 23/10/22 | R 18 Club Olimpia 2 Club General Caballero Jlm 1 G01:30 | 16/10/22 | R 17 Club General Caballero Jlm 2 Sportivo Ameliano 0 G23:00 | 12/10/22 | R 16 Tacuary Asuncion 0 Club General Caballero Jlm 3 |
| 7 | |  Guairena FC | 22 | 7 | 6 | 9 | 26 | 31 | -5 | 27 | M01:00 | 13/11/22 | R 22 Guairena FC 1 Cerro Porteno 3 M23:00 | 06/11/22 | R 21 Libertad Asuncion 4 Guairena FC 2 G23:00 | 30/10/22 | R 20 Guairena FC 1 Club Guarani 0 M23:00 | 27/10/22 | R 19 Nacional Asuncion 3 Guairena FC 0 B23:00 | 21/10/22 | R 18 Guairena FC 0 Sol De America 0 B01:00 | 15/10/22 | R 17 12 De Octubre De Itaugua 0 Guairena FC 0 |
| 8 | |  Sportivo Ameliano | 21 | 8 | 2 | 11 | 25 | 30 | -5 | 26 | G01:30 | 09/11/22 | R 21 Nacional Asuncion 0 Sportivo Ameliano 2 G02:00 | 02/11/22 | R 20 Sportivo Ameliano 2 Sol De America 1 M23:30 | 26/10/22 | R 19 12 De Octubre De Itaugua 4 Sportivo Ameliano 0 G23:00 | 22/10/22 | R 18 Sportivo Ameliano 3 Resistencia FC 2 M01:30 | 16/10/22 | R 17 Club General Caballero Jlm 2 Sportivo Ameliano 0 M23:00 | 09/10/22 | R 16 Sportivo Ameliano 0 Club Olimpia 2 |
| 9 | |  Club Guarani | 21 | 6 | 5 | 10 | 21 | 28 | -7 | 23 | G01:30 | 07/11/22 | R 21 Club Guarani 2 Tacuary Asuncion 1 M23:00 | 30/10/22 | R 20 Guairena FC 1 Club Guarani 0 M23:00 | 27/10/22 | R 19 Club Guarani 1 Libertad Asuncion 2 M23:00 | 23/10/22 | R 18 Club Guarani 1 Cerro Porteno 2 M02:00 | 17/10/22 | R 17 Nacional Asuncion 2 Club Guarani 0 G23:00 | 13/10/22 | R 16 Club Guarani 4 Sol De America 1 |
| 10 | |  Sol De America | 21 | 5 | 5 | 11 | 21 | 33 | -12 | 20 | M01:30 | 09/11/22 | R 21 Sol De America 0 Club Olimpia 2 M02:00 | 02/11/22 | R 20 Sportivo Ameliano 2 Sol De America 1 B01:00 | 26/10/22 | R 19 Sol De America 2 Tacuary Asuncion 2 B23:00 | 21/10/22 | R 18 Guairena FC 0 Sol De America 0 B01:00 | 18/10/22 | R 17 Sol De America 1 Libertad Asuncion 1 M23:00 | 13/10/22 | R 16 Club Guarani 4 Sol De America 1 |
| 11 | |  Resistencia FC | 21 | 5 | 5 | 11 | 16 | 32 | -16 | 20 | M01:30 | 08/11/22 | R 21 Cerro Porteno 1 Resistencia FC 0 M23:30 | 01/11/22 | R 20 Club General Caballero Jlm 1 Resistencia FC 0 M16:00 | 27/10/22 | R 19 Resistencia FC 1 Club Olimpia 6 M23:00 | 22/10/22 | R 18 Sportivo Ameliano 3 Resistencia FC 2 M23:00 | 15/10/22 | R 17 Resistencia FC 0 Tacuary Asuncion 3 M23:00 | 10/10/22 | R 16 Guairena FC 3 Resistencia FC 2 |
| 12 | |  12 De Octubre De Itaugua | 21 | 3 | 2 | 16 | 16 | 37 | -21 | 11 | M01:30 | 09/11/22 | R 21 12 De Octubre De Itaugua 0 Club General Caballero Jlm 3 M01:30 | 31/10/22 | R 20 Club Olimpia 3 12 De Octubre De Itaugua 1 G23:30 | 26/10/22 | R 19 12 De Octubre De Itaugua 4 Sportivo Ameliano 0 M01:30 | 22/10/22 | R 18 Tacuary Asuncion 5 12 De Octubre De Itaugua 1 B01:00 | 15/10/22 | R 17 12 De Octubre De Itaugua 0 Guairena FC 0 B01:30 | 10/10/22 | R 16 Libertad Asuncion 2 12 De Octubre De Itaugua 2 |
