| 1 | |  CD Universidad Catolica | 32 | 22 | 2 | 8 | 65 | 34 | 31 | 68 | G00:00 | 05/12/21 | R 34  CD Everton Vina Del Mar 0 CD Universidad Catolica 3 G00:00 | 29/11/21 | R 33 CD Universidad Catolica 2 Huachipato 0 G21:30 | 13/11/21 | R 32 La Serena 0 CD Universidad Catolica 2 G18:00 | 07/11/21 | R 31 CD Universidad Catolica 1 U. Chile 0 G00:00 | 05/11/21 | R 30 CD Universidad Catolica 4 Antofagasta 0 G00:00 | 01/11/21 | R 29 O´higgins 1 CD Universidad Catolica 3 |
| 2 | |  Colo Colo | 32 | 19 | 5 | 8 | 49 | 26 | 23 | 62 | M00:00 | 05/12/21 | R 34 Antofagasta 1 Colo Colo 0 M00:00 | 29/11/21 | R 33 Colo Colo 0 Union Espanola 1 B00:30 | 15/11/21 | R 32 Curico Unido 0 Colo Colo 0 G01:00 | 11/11/21 | R 31 Colo Colo 1 CD Melipilla 0 G00:00 | 07/11/21 | R 31 Colo Colo 3 Santiago Wanderers 0 M00:00 | 29/10/21 | R 29 Audax Italiano 2 Colo Colo 0 |
| 3 | |  Audax Italiano | 32 | 14 | 12 | 6 | 39 | 31 | 8 | 54 | B00:00 | 06/12/21 | R 34 Audax Italiano 1 Curico Unido 1 B18:00 | 28/11/21 | R 33 Santiago Wanderers 2 Audax Italiano 2 B18:30 | 14/11/21 | R 32 Audax Italiano 0 Antofagasta 0 G03:00 | 03/11/21 | R 30 CD Everton Vina Del Mar 1 Audax Italiano 2 G00:00 | 29/10/21 | R 29 Audax Italiano 2 Colo Colo 0 B02:00 | 25/10/21 | R 28 Huachipato 0 Audax Italiano 0 |
| 4 | |  Deportes Union La Calera | 32 | 15 | 6 | 11 | 41 | 40 | 1 | 51 | M00:00 | 06/12/21 | R 34 U. Chile 3 Deportes Union La Calera 2 M00:00 | 29/11/21 | R 33 Deportes Union La Calera 1 La Serena 2 G03:00 | 14/11/21 | R 32 CD Everton Vina Del Mar 1 Deportes Union La Calera 2 M03:00 | 08/11/21 | R 31 Deportes Union La Calera 0 Huachipato 2 G21:30 | 04/11/21 | R 30 Palestino 1 Deportes Union La Calera 2 M02:30 | 01/11/21 | R 29 Deportes Union La Calera 2 CD Melipilla 3 |
| 5 | |  Union Espanola | 32 | 15 | 3 | 14 | 48 | 50 | -2 | 48 | M00:00 | 06/12/21 | R 34 Union Espanola 0 Cobresal 1 G00:00 | 29/11/21 | R 33 Colo Colo 0 Union Espanola 1 M18:30 | 13/11/21 | R 32 Nublense 6 Union Espanola 1 M02:30 | 09/11/21 | R 31 Union Espanola 1 Palestino 3 M00:30 | 04/11/21 | R 30 Huachipato 1 Union Espanola 0 G00:30 | 31/10/21 | R 29 Union Espanola 3 CD Everton Vina Del Mar 2 |
| 6 | |  Antofagasta | 32 | 12 | 11 | 9 | 34 | 36 | -2 | 47 | G00:00 | 05/12/21 | R 34 Antofagasta 1 Colo Colo 0 B00:00 | 28/11/21 | R 33 O´higgins 0 Antofagasta 0 B18:30 | 14/11/21 | R 32 Audax Italiano 0 Antofagasta 0 B00:00 | 09/11/21 | R 31 Antofagasta 0 La Serena 0 M00:00 | 05/11/21 | R 30 CD Universidad Catolica 4 Antofagasta 0 G18:30 | 31/10/21 | R 29 Antofagasta 2 Nublense 1 |
| 7 | |  Nublense | 32 | 11 | 11 | 10 | 49 | 37 | 12 | 44 | G00:00 | 05/12/21 | R 34 Palestino 1 Nublense 4 G18:30 | 13/11/21 | R 32 Nublense 6 Union Espanola 1 B22:00 | 07/11/21 | R 31 O´higgins 1 Nublense 1 G02:30 | 05/11/21 | R 30 Nublense 1 U. Chile 0 M18:30 | 31/10/21 | R 29 Antofagasta 2 Nublense 1 B00:00 | 24/10/21 | R 28 Nublense 1 CD Everton Vina Del Mar 1 |
| 8 | |  Palestino | 32 | 11 | 8 | 13 | 48 | 50 | -2 | 41 | M00:00 | 05/12/21 | R 34 Palestino 1 Nublense 4 B00:00 | 29/11/21 | R 33 Curico Unido 1 Palestino 1 G22:00 | 14/11/21 | R 32 Palestino 2 Cobresal 1 G02:30 | 09/11/21 | R 31 Union Espanola 1 Palestino 3 M21:30 | 04/11/21 | R 30 Palestino 1 Deportes Union La Calera 2 B21:30 | 29/10/21 | R 29 Santiago Wanderers 1 Palestino 1 |
| 9 | |  Cobresal | 32 | 11 | 7 | 14 | 40 | 39 | 1 | 40 | G00:00 | 06/12/21 | R 34 Union Espanola 0 Cobresal 1 B00:00 | 28/11/21 | R 33 Cobresal 0 U. Chile 0 M22:00 | 14/11/21 | R 32 Palestino 2 Cobresal 1 B00:30 | 08/11/21 | R 31 Cobresal 2 CD Everton Vina Del Mar 2 M22:00 | 03/11/21 | R 30 CD Melipilla 2 Cobresal 1 M17:00 | 26/10/21 | R 28 Cobresal 2 O´higgins 3 |
| 10 | |  La Serena | 32 | 9 | 12 | 11 | 40 | 42 | -2 | 39 | B00:00 | 05/12/21 | R 34 La Serena 0 Santiago Wanderers 0 G00:00 | 29/11/21 | R 33 Deportes Union La Calera 1 La Serena 2 M21:30 | 13/11/21 | R 32 La Serena 0 CD Universidad Catolica 2 B00:00 | 09/11/21 | R 31 Antofagasta 0 La Serena 0 B23:50 | 29/10/21 | R 29 La Serena 2 Huachipato 2 B22:00 | 25/10/21 | R 28 Palestino 3 La Serena 3 |
| 11 | |  U. Chile | 32 | 10 | 9 | 13 | 34 | 37 | -3 | 39 | G00:00 | 06/12/21 | R 34 U. Chile 3 Deportes Union La Calera 2 B00:00 | 28/11/21 | R 33 Cobresal 0 U. Chile 0 B02:00 | 16/11/21 | R 32 U. Chile 0 O´higgins 0 M18:00 | 07/11/21 | R 31 CD Universidad Catolica 1 U. Chile 0 M02:30 | 05/11/21 | R 30 Nublense 1 U. Chile 0 M22:00 | 30/10/21 | R 29 U. Chile 1 Curico Unido 2 |
| 12 | |  CD Everton Vina Del Mar | 32 | 10 | 9 | 13 | 29 | 35 | -6 | 39 | M00:00 | 05/12/21 | R 34 CD Everton Vina Del Mar 0 CD Universidad Catolica 3 M00:00 | 28/11/21 | R 33 CD Melipilla 1 CD Everton Vina Del Mar 0 M03:00 | 14/11/21 | R 32 CD Everton Vina Del Mar 1 Deportes Union La Calera 2 B00:30 | 08/11/21 | R 31 Cobresal 2 CD Everton Vina Del Mar 2 M03:00 | 03/11/21 | R 30 CD Everton Vina Del Mar 1 Audax Italiano 2 M00:30 | 31/10/21 | R 29 Union Espanola 3 CD Everton Vina Del Mar 2 |
| 13 | |  O´higgins | 32 | 9 | 11 | 12 | 31 | 41 | -10 | 38 | B00:00 | 28/11/21 | R 33 O´higgins 0 Antofagasta 0 B02:00 | 16/11/21 | R 32 U. Chile 0 O´higgins 0 B22:00 | 07/11/21 | R 31 O´higgins 1 Nublense 1 G03:00 | 04/11/21 | R 30 Curico Unido 0 O´higgins 2 M00:00 | 01/11/21 | R 29 O´higgins 1 CD Universidad Catolica 3 G17:00 | 26/10/21 | R 28 Cobresal 2 O´higgins 3 |
| 14 | |  Curico Unido | 32 | 8 | 13 | 11 | 37 | 39 | -2 | 37 | B00:00 | 06/12/21 | R 34 Audax Italiano 1 Curico Unido 1 B00:00 | 29/11/21 | R 33 Curico Unido 1 Palestino 1 B00:30 | 15/11/21 | R 32 Curico Unido 0 Colo Colo 0 G01:00 | 10/11/21 | R 31 Santiago Wanderers 0 Curico Unido 3 M03:00 | 04/11/21 | R 30 Curico Unido 0 O´higgins 2 G22:00 | 30/10/21 | R 29 U. Chile 1 Curico Unido 2 |
| 15 | |  Huachipato | 32 | 8 | 13 | 11 | 36 | 41 | -5 | 37 | G00:00 | 06/12/21 | R 34 Huachipato 3 CD Melipilla 1 M00:00 | 29/11/21 | R 33 CD Universidad Catolica 2 Huachipato 0 G23:30 | 15/11/21 | R 32 Huachipato 2 Santiago Wanderers 0 G03:00 | 08/11/21 | R 31 Deportes Union La Calera 0 Huachipato 2 |
| 16 | |  CD Melipilla | 32 | 10 | 8 | 14 | 39 | 51 | -12 | 32 | M00:00 | 06/12/21 | R 34 Huachipato 3 CD Melipilla 1 G00:00 | 28/11/21 | R 33 CD Melipilla 1 CD Everton Vina Del Mar 0 M01:00 | 11/11/21 | R 31 Colo Colo 1 CD Melipilla 0 G22:00 | 03/11/21 | R 30 CD Melipilla 2 Cobresal 1 G02:30 | 01/11/21 | R 29 Deportes Union La Calera 2 CD Melipilla 3 G18:00 | 24/10/21 | R 28 CD Melipilla 3 U. Chile 0 |
| 17 | |  Santiago Wanderers | 32 | 5 | 6 | 21 | 24 | 54 | -30 | 21 | B00:00 | 05/12/21 | R 34 La Serena 0 Santiago Wanderers 0 B18:00 | 28/11/21 | R 33 Santiago Wanderers 2 Audax Italiano 2 M23:30 | 15/11/21 | R 32 Huachipato 2 Santiago Wanderers 0 M01:00 | 10/11/21 | R 31 Santiago Wanderers 0 Curico Unido 3 M00:00 | 07/11/21 | R 31 Colo Colo 3 Santiago Wanderers 0 B21:30 | 29/10/21 | R 29 Santiago Wanderers 1 Palestino 1 |
