| 1 | |  Manchester City FC | 38 | 27 | 5 | 6 | 83 | 32 | 51 | 86 | G18:00 | 23/05/21 | R 38  Manchester City FC 5 Everton FC 0 M21:00 | 18/05/21 | R 37 Brighton & Hove Albion FC 3 Manchester City FC 2 G22:00 | 14/05/21 | R 36 Newcastle United FC 3 Manchester City FC 4 M19:30 | 08/05/21 | R 35 Manchester City FC 1 Chelsea 2 G14:30 | 01/05/21 | R 34 Crystal Palace FC 0 Manchester City FC 2 G22:15 | 21/04/21 | R 32 Aston Villa 1 Manchester City FC 2 |
| 2 | |  Manchester United FC | 38 | 21 | 11 | 6 | 73 | 44 | 29 | 74 | G18:00 | 23/05/21 | R 38 Wolverhampton Wanderers FC 1 Manchester United FC 2 B20:00 | 18/05/21 | R 37 Manchester United FC 1 Fulham FC 1 M22:15 | 13/05/21 | R 34 Manchester United FC 2 Liverpool 4 M20:00 | 11/05/21 | R 36 Manchester United FC 1 Leicester City FC 2 G16:05 | 09/05/21 | R 35 Aston Villa 1 Manchester United FC 3 B16:00 | 25/04/21 | R 33 Leeds United 0 Manchester United FC 0 |
| 3 | |  Liverpool | 38 | 20 | 9 | 9 | 68 | 42 | 26 | 69 | G18:00 | 23/05/21 | R 38 Liverpool 2 Crystal Palace FC 0 G22:15 | 19/05/21 | R 37 Burnley 0 Liverpool 3 G18:30 | 16/05/21 | R 36 West Bromwich Albion 1 Liverpool 2 G22:15 | 13/05/21 | R 34 Manchester United FC 2 Liverpool 4 G22:15 | 08/05/21 | R 35 Liverpool 2 Southampton 0 B14:30 | 24/04/21 | R 33 Liverpool 1 Newcastle United FC 1 |
| 4 | |  Chelsea | 38 | 19 | 10 | 9 | 58 | 36 | 22 | 67 | M18:00 | 23/05/21 | R 38 Aston Villa 2 Chelsea 1 G22:15 | 18/05/21 | R 37 Chelsea 2 Leicester City FC 1 M22:15 | 12/05/21 | R 36 Chelsea 0 Arsenal 1 G19:30 | 08/05/21 | R 35 Manchester City FC 1 Chelsea 2 G19:30 | 01/05/21 | R 34 Chelsea 2 Fulham FC 0 G19:30 | 24/04/21 | R 33 West Ham United FC 0 Chelsea 1 |
| 5 | |  Leicester City FC | 38 | 20 | 6 | 12 | 68 | 50 | 18 | 66 | M18:00 | 23/05/21 | R 38 Leicester City FC 2 Tottenham Hotspur FC 4 M22:15 | 18/05/21 | R 37 Chelsea 2 Leicester City FC 1 G20:00 | 11/05/21 | R 36 Manchester United FC 1 Leicester City FC 2 M22:00 | 07/05/21 | R 35 Leicester City FC 2 Newcastle United FC 4 B22:00 | 30/04/21 | R 34 Southampton 1 Leicester City FC 1 G22:00 | 26/04/21 | R 33 Leicester City FC 2 Crystal Palace FC 1 |
| 6 | |  West Ham United FC | 38 | 19 | 8 | 11 | 62 | 47 | 15 | 65 | G18:00 | 23/05/21 | R 38 West Ham United FC 3 Southampton 0 G22:15 | 19/05/21 | R 37 West Bromwich Albion 1 West Ham United FC 3 B22:00 | 15/05/21 | R 36 Brighton & Hove Albion FC 1 West Ham United FC 1 M18:30 | 09/05/21 | R 35 West Ham United FC 0 Everton FC 1 G22:15 | 03/05/21 | R 34 Burnley 1 West Ham United FC 2 M19:30 | 24/04/21 | R 33 West Ham United FC 0 Chelsea 1 |
| 7 | |  Tottenham Hotspur FC | 38 | 18 | 8 | 12 | 68 | 45 | 23 | 62 | G18:00 | 23/05/21 | R 38 Leicester City FC 2 Tottenham Hotspur FC 4 M20:00 | 19/05/21 | R 37 Tottenham Hotspur FC 1 Aston Villa 2 G16:05 | 16/05/21 | R 36 Tottenham Hotspur FC 2 Wolverhampton Wanderers FC 0 M14:30 | 08/05/21 | R 35 Leeds United 3 Tottenham Hotspur FC 1 G21:15 | 02/05/21 | R 34 Tottenham Hotspur FC 4 Sheffield United FC 0 G20:00 | 21/04/21 | R 29 Tottenham Hotspur FC 2 Southampton 1 |
| 8 | |  Arsenal | 38 | 18 | 7 | 13 | 55 | 39 | 16 | 61 | G18:00 | 23/05/21 | R 38 Arsenal 2 Brighton & Hove Albion FC 0 G21:00 | 19/05/21 | R 37 Crystal Palace FC 1 Arsenal 3 G22:15 | 12/05/21 | R 36 Chelsea 0 Arsenal 1 G21:00 | 09/05/21 | R 35 Arsenal 3 West Bromwich Albion 1 G16:00 | 02/05/21 | R 34 Newcastle United FC 0 Arsenal 2 M22:00 | 23/04/21 | R 33 Arsenal 0 Everton FC 1 |
| 9 | |  Leeds United | 38 | 18 | 5 | 15 | 62 | 54 | 8 | 59 | G18:00 | 23/05/21 | R 38 Leeds United 3 West Bromwich Albion 1 G20:00 | 18/05/21 | R 37 Southampton 0 Leeds United 2 G14:30 | 15/05/21 | R 36 Burnley 0 Leeds United 4 G14:30 | 08/05/21 | R 35 Leeds United 3 Tottenham Hotspur FC 1 M17:00 | 01/05/21 | R 34 Brighton & Hove Albion FC 2 Leeds United 0 B16:00 | 25/04/21 | R 33 Leeds United 0 Manchester United FC 0 |
| 10 | |  Everton FC | 38 | 17 | 8 | 13 | 47 | 48 | -1 | 59 | M18:00 | 23/05/21 | R 38 Manchester City FC 5 Everton FC 0 G20:00 | 19/05/21 | R 37 Everton FC 1 Wolverhampton Wanderers FC 0 M21:00 | 16/05/21 | R 36 Everton FC 0 Sheffield United FC 1 B20:00 | 13/05/21 | R 19 Aston Villa 0 Everton FC 0 G18:30 | 09/05/21 | R 35 West Ham United FC 0 Everton FC 1 M22:00 | 01/05/21 | R 34 Everton FC 1 Aston Villa 2 |
| 11 | |  Aston Villa | 38 | 16 | 7 | 15 | 55 | 46 | 9 | 55 | G18:00 | 23/05/21 | R 38 Aston Villa 2 Chelsea 1 G20:00 | 19/05/21 | R 37 Tottenham Hotspur FC 1 Aston Villa 2 M14:00 | 16/05/21 | R 36 Crystal Palace FC 3 Aston Villa 2 B20:00 | 13/05/21 | R 19 Aston Villa 0 Everton FC 0 M16:05 | 09/05/21 | R 35 Aston Villa 1 Manchester United FC 3 G22:00 | 01/05/21 | R 34 Everton FC 1 Aston Villa 2 |
| 12 | |  Newcastle United FC | 38 | 12 | 9 | 17 | 46 | 62 | -16 | 45 | G18:00 | 23/05/21 | R 38 Fulham FC 0 Newcastle United FC 2 G20:00 | 19/05/21 | R 37 Newcastle United FC 1 Sheffield United FC 0 M22:00 | 14/05/21 | R 36 Newcastle United FC 3 Manchester City FC 4 G22:00 | 07/05/21 | R 35 Leicester City FC 2 Newcastle United FC 4 M16:00 | 02/05/21 | R 34 Newcastle United FC 0 Arsenal 2 B14:30 | 24/04/21 | R 33 Liverpool 1 Newcastle United FC 1 |
| 13 | |  Wolverhampton Wanderers FC | 38 | 12 | 9 | 17 | 36 | 52 | -16 | 45 | M18:00 | 23/05/21 | R 38 Wolverhampton Wanderers FC 1 Manchester United FC 2 M20:00 | 19/05/21 | R 37 Everton FC 1 Wolverhampton Wanderers FC 0 M16:05 | 16/05/21 | R 36 Tottenham Hotspur FC 2 Wolverhampton Wanderers FC 0 G14:00 | 09/05/21 | R 35 Wolverhampton Wanderers FC 2 Brighton & Hove Albion FC 1 B20:00 | 03/05/21 | R 34 West Bromwich Albion 1 Wolverhampton Wanderers FC 1 M14:00 | 25/04/21 | R 33 Wolverhampton Wanderers FC 0 Burnley 4 |
| 14 | |  Crystal Palace FC | 38 | 12 | 8 | 18 | 41 | 66 | -25 | 44 | M18:00 | 23/05/21 | R 38 Liverpool 2 Crystal Palace FC 0 M21:00 | 19/05/21 | R 37 Crystal Palace FC 1 Arsenal 3 G14:00 | 16/05/21 | R 36 Crystal Palace FC 3 Aston Villa 2 M22:15 | 11/05/21 | R 32 Southampton 3 Crystal Palace FC 1 G17:00 | 08/05/21 | R 35 Sheffield United FC 0 Crystal Palace FC 2 M14:30 | 01/05/21 | R 34 Crystal Palace FC 0 Manchester City FC 2 |
| 15 | |  Southampton | 38 | 12 | 7 | 19 | 47 | 68 | -21 | 43 | M18:00 | 23/05/21 | R 38 West Ham United FC 3 Southampton 0 M20:00 | 18/05/21 | R 37 Southampton 0 Leeds United 2 G17:00 | 15/05/21 | R 36 Southampton 3 Fulham FC 1 G22:15 | 11/05/21 | R 32 Southampton 3 Crystal Palace FC 1 M22:15 | 08/05/21 | R 35 Liverpool 2 Southampton 0 B22:00 | 30/04/21 | R 34 Southampton 1 Leicester City FC 1 |
| 16 | |  Brighton & Hove Albion FC | 38 | 9 | 14 | 15 | 40 | 46 | -6 | 41 | M18:00 | 23/05/21 | R 38 Arsenal 2 Brighton & Hove Albion FC 0 G21:00 | 18/05/21 | R 37 Brighton & Hove Albion FC 3 Manchester City FC 2 B22:00 | 15/05/21 | R 36 Brighton & Hove Albion FC 1 West Ham United FC 1 M14:00 | 09/05/21 | R 35 Wolverhampton Wanderers FC 2 Brighton & Hove Albion FC 1 G17:00 | 01/05/21 | R 34 Brighton & Hove Albion FC 2 Leeds United 0 M22:00 | 24/04/21 | R 33 Sheffield United FC 1 Brighton & Hove Albion FC 0 |
| 17 | |  Burnley | 38 | 10 | 9 | 19 | 33 | 55 | -22 | 39 | M18:00 | 23/05/21 | R 38 Sheffield United FC 1 Burnley 0 M22:15 | 19/05/21 | R 37 Burnley 0 Liverpool 3 M14:30 | 15/05/21 | R 36 Burnley 0 Leeds United 4 G22:00 | 10/05/21 | R 35 Fulham FC 0 Burnley 2 M22:15 | 03/05/21 | R 34 Burnley 1 West Ham United FC 2 G14:00 | 25/04/21 | R 33 Wolverhampton Wanderers FC 0 Burnley 4 |
| 18 | |  Fulham FC | 38 | 5 | 13 | 20 | 27 | 53 | -26 | 28 | M18:00 | 23/05/21 | R 38 Fulham FC 0 Newcastle United FC 2 B20:00 | 18/05/21 | R 37 Manchester United FC 1 Fulham FC 1 M17:00 | 15/05/21 | R 36 Southampton 3 Fulham FC 1 M22:00 | 10/05/21 | R 35 Fulham FC 0 Burnley 2 M19:30 | 01/05/21 | R 34 Chelsea 2 Fulham FC 0 B15:30 | 18/04/21 | R 32 Arsenal 1 Fulham FC 1 |
| 19 | |  West Bromwich Albion | 38 | 5 | 11 | 22 | 35 | 76 | -41 | 26 | M18:00 | 23/05/21 | R 38 Leeds United 3 West Bromwich Albion 1 M22:15 | 19/05/21 | R 37 West Bromwich Albion 1 West Ham United FC 3 M18:30 | 16/05/21 | R 36 West Bromwich Albion 1 Liverpool 2 M21:00 | 09/05/21 | R 35 Arsenal 3 West Bromwich Albion 1 B20:00 | 03/05/21 | R 34 West Bromwich Albion 1 Wolverhampton Wanderers FC 1 B21:00 | 25/04/21 | R 33 Aston Villa 2 West Bromwich Albion 2 |
| 20 | |  Sheffield United FC | 38 | 7 | 2 | 29 | 20 | 63 | -43 | 23 | G18:00 | 23/05/21 | R 38 Sheffield United FC 1 Burnley 0 M20:00 | 19/05/21 | R 37 Newcastle United FC 1 Sheffield United FC 0 G21:00 | 16/05/21 | R 36 Everton FC 0 Sheffield United FC 1 M17:00 | 08/05/21 | R 35 Sheffield United FC 0 Crystal Palace FC 2 M21:15 | 02/05/21 | R 34 Tottenham Hotspur FC 4 Sheffield United FC 0 G22:00 | 24/04/21 | R 33 Sheffield United FC 1 Brighton & Hove Albion FC 0 |
