| 1 | |  Hamrun Spartans FC | 23 | 17 | 5 | 1 | 56 | 20 | 36 | 56 | G16:00 | 06/03/21 | R 23  Hamrun Spartans FC 1 Hibernians 0 G20:00 | 27/02/21 | R 22 Gzira United Fc 1 Hamrun Spartans FC 2 G21:00 | 21/02/21 | R 21 Hamrun Spartans FC 3 Balzan FC 2 G16:00 | 13/02/21 | R 20 Birkirkara 0 Hamrun Spartans FC 2 G20:00 | 07/02/21 | R 19 Hamrun Spartans FC 3 Gudja United 1 G20:00 | 30/01/21 | R 18 Senglea Athletic 0 Hamrun Spartans FC 1 |
| 2 | |  Hibernians | 23 | 16 | 3 | 4 | 53 | 20 | 33 | 51 | M16:00 | 06/03/21 | R 23 Hamrun Spartans FC 1 Hibernians 0 G20:00 | 27/02/21 | R 22 Hibernians 2 Zejtun Corinthians FC 0 G17:00 | 21/02/21 | R 21 Lija Athletic 0 Hibernians 5 G16:00 | 13/02/21 | R 20 Hibernians 2 Mosta FC 0 G16:00 | 07/02/21 | R 19 Valetta 1 Hibernians 4 G16:00 | 30/01/21 | R 18 Hibernians 2 Tarxien Rainbows FC 0 |
| 3 | |  Gzira United Fc | 23 | 14 | 4 | 5 | 49 | 21 | 28 | 46 | M20:00 | 06/03/21 | R 23 Sliema Wanderers 2 Gzira United Fc 0 M20:00 | 27/02/21 | R 22 Gzira United Fc 1 Hamrun Spartans FC 2 G20:00 | 20/02/21 | R 21 Zejtun Corinthians FC 0 Gzira United Fc 4 G16:00 | 14/02/21 | R 20 Gzira United Fc 1 Lija Athletic 0 G20:00 | 06/02/21 | R 19 Mosta FC 1 Gzira United Fc 2 G19:00 | 03/02/21 | R 15 Gudja United 0 Gzira United Fc 3 |
| 4 | |  Birkirkara | 23 | 13 | 5 | 5 | 45 | 25 | 20 | 44 | G16:00 | 06/03/21 | R 23 Tarxien Rainbows FC 0 Birkirkara 3 G16:00 | 27/02/21 | R 22 Birkirkara 2 Floriana FC 0 B16:00 | 20/02/21 | R 21 Sliema Wanderers 2 Birkirkara 2 G20:30 | 17/02/21 | R 16 Birkirkara 2 Valetta 0 M16:00 | 13/02/21 | R 20 Birkirkara 0 Hamrun Spartans FC 2 G19:00 | 05/02/21 | R 19 Zejtun Corinthians FC 0 Birkirkara 3 |
| 5 | |  Sliema Wanderers | 23 | 12 | 4 | 7 | 39 | 31 | 8 | 40 | G20:00 | 06/03/21 | R 23 Sliema Wanderers 2 Gzira United Fc 0 M16:00 | 28/02/21 | R 22 Balzan FC 5 Sliema Wanderers 1 B16:00 | 20/02/21 | R 21 Sliema Wanderers 2 Birkirkara 2 B21:00 | 14/02/21 | R 20 Gudja United 1 Sliema Wanderers 1 G20:00 | 06/02/21 | R 19 Sliema Wanderers 3 Senglea Athletic 1 B20:30 | 03/02/21 | R 15 Valetta 0 Sliema Wanderers 0 |
| 6 | |  Mosta FC | 23 | 10 | 6 | 7 | 41 | 36 | 5 | 36 | G20:00 | 06/03/21 | R 23 Mosta FC 5 Senglea Athletic 1 G16:00 | 27/02/21 | R 22 St Lucia FC 2 Mosta FC 3 B20:00 | 21/02/21 | R 21 Mosta FC 0 Sirens FC 0 G23:00 | 17/02/21 | R 16 Gudja United 0 Mosta FC 1 M16:00 | 13/02/21 | R 20 Hibernians 2 Mosta FC 0 M20:00 | 06/02/21 | R 19 Mosta FC 1 Gzira United Fc 2 |
| 7 | |  Valetta | 23 | 9 | 6 | 8 | 27 | 35 | -8 | 33 | M20:00 | 07/03/21 | R 23 Valetta 2 Gudja United 4 G20:00 | 28/02/21 | R 22 Senglea Athletic 1 Valetta 3 G16:00 | 21/02/21 | R 21 Valetta 1 St Lucia FC 0 M20:30 | 17/02/21 | R 16 Birkirkara 2 Valetta 0 G17:00 | 14/02/21 | R 20 Sirens FC 0 Valetta 1 M16:00 | 07/02/21 | R 19 Valetta 1 Hibernians 4 |
| 8 | |  St Lucia FC | 23 | 7 | 8 | 8 | 38 | 35 | 3 | 29 | M20:00 | 06/03/21 | R 23 Lija Athletic 3 St Lucia FC 1 M16:00 | 27/02/21 | R 22 St Lucia FC 2 Mosta FC 3 M16:00 | 21/02/21 | R 21 Valetta 1 St Lucia FC 0 G20:00 | 13/02/21 | R 20 St Lucia FC 7 Tarxien Rainbows FC 0 B23:00 | 05/02/21 | R 19 Floriana FC 1 St Lucia FC 1 M23:00 | 29/01/21 | R 18 St Lucia FC 0 Sliema Wanderers 1 |
| 9 | |  Sirens FC | 23 | 7 | 7 | 9 | 27 | 35 | -8 | 28 | B16:00 | 07/03/21 | R 23 Zejtun Corinthians FC 1 Sirens FC 1 B23:00 | 26/02/21 | R 22 Sirens FC 1 Lija Athletic 1 B20:00 | 21/02/21 | R 21 Mosta FC 0 Sirens FC 0 M17:00 | 14/02/21 | R 20 Sirens FC 0 Valetta 1 M16:00 | 06/02/21 | R 19 Tarxien Rainbows FC 3 Sirens FC 1 G16:00 | 30/01/21 | R 18 Sirens FC 2 Floriana FC 1 |
| 10 | |  Balzan FC | 23 | 6 | 9 | 8 | 31 | 29 | 2 | 27 | G19:00 | 10/03/21 | R 20 Balzan FC 3 Zejtun Corinthians FC 1 B16:00 | 06/03/21 | R 23 Floriana FC 0 Balzan FC 0 G16:00 | 28/02/21 | R 22 Balzan FC 5 Sliema Wanderers 1 M21:00 | 21/02/21 | R 21 Hamrun Spartans FC 3 Balzan FC 2 B16:00 | 06/02/21 | R 19 Lija Athletic 1 Balzan FC 1 G19:00 | 29/01/21 | R 18 Balzan FC 4 Mosta FC 1 |
| 11 | |  Gudja United | 23 | 8 | 3 | 12 | 29 | 35 | -6 | 27 | G20:00 | 07/03/21 | R 23 Valetta 2 Gudja United 4 M19:00 | 26/02/21 | R 22 Gudja United 0 Tarxien Rainbows FC 2 M20:00 | 20/02/21 | R 21 Floriana FC 1 Gudja United 0 M23:00 | 17/02/21 | R 16 Gudja United 0 Mosta FC 1 B21:00 | 14/02/21 | R 20 Gudja United 1 Sliema Wanderers 1 M20:00 | 07/02/21 | R 19 Hamrun Spartans FC 3 Gudja United 1 |
| 12 | |  Floriana FC | 23 | 7 | 6 | 10 | 26 | 34 | -8 | 27 | B16:00 | 06/03/21 | R 23 Floriana FC 0 Balzan FC 0 M16:00 | 27/02/21 | R 22 Birkirkara 2 Floriana FC 0 G20:00 | 20/02/21 | R 21 Floriana FC 1 Gudja United 0 G20:00 | 13/02/21 | R 20 Senglea Athletic 0 Floriana FC 2 B23:00 | 05/02/21 | R 19 Floriana FC 1 St Lucia FC 1 M16:00 | 30/01/21 | R 18 Sirens FC 2 Floriana FC 1 |
| 13 | |  Zejtun Corinthians FC | 23 | 6 | 6 | 11 | 28 | 40 | -12 | 24 | M19:00 | 10/03/21 | R 20 Balzan FC 3 Zejtun Corinthians FC 1 B16:00 | 07/03/21 | R 23 Zejtun Corinthians FC 1 Sirens FC 1 M20:00 | 27/02/21 | R 22 Hibernians 2 Zejtun Corinthians FC 0 M20:00 | 20/02/21 | R 21 Zejtun Corinthians FC 0 Gzira United Fc 4 M19:00 | 05/02/21 | R 19 Zejtun Corinthians FC 0 Birkirkara 3 G20:00 | 30/01/21 | R 18 Gudja United 0 Zejtun Corinthians FC 1 |
| 14 | |  Tarxien Rainbows FC | 23 | 6 | 3 | 14 | 25 | 48 | -23 | 21 | M16:00 | 06/03/21 | R 23 Tarxien Rainbows FC 0 Birkirkara 3 G19:00 | 26/02/21 | R 22 Gudja United 0 Tarxien Rainbows FC 2 G16:00 | 20/02/21 | R 21 Tarxien Rainbows FC 4 Senglea Athletic 2 M20:00 | 13/02/21 | R 20 St Lucia FC 7 Tarxien Rainbows FC 0 G16:00 | 06/02/21 | R 19 Tarxien Rainbows FC 3 Sirens FC 1 M23:00 | 03/02/21 | R 15 Lija Athletic 2 Tarxien Rainbows FC 0 |
| 15 | |  Lija Athletic | 23 | 5 | 5 | 13 | 25 | 46 | -21 | 20 | G20:00 | 06/03/21 | R 23 Lija Athletic 3 St Lucia FC 1 B23:00 | 26/02/21 | R 22 Sirens FC 1 Lija Athletic 1 M17:00 | 21/02/21 | R 21 Lija Athletic 0 Hibernians 5 G19:00 | 17/02/21 | R 16 Senglea Athletic 1 Lija Athletic 3 M16:00 | 14/02/21 | R 20 Gzira United Fc 1 Lija Athletic 0 B16:00 | 06/02/21 | R 19 Lija Athletic 1 Balzan FC 1 |
| 16 | |  Senglea Athletic | 23 | 0 | 2 | 21 | 13 | 62 | -49 | 2 | M20:00 | 06/03/21 | R 23 Mosta FC 5 Senglea Athletic 1 M20:00 | 28/02/21 | R 22 Senglea Athletic 1 Valetta 3 M16:00 | 20/02/21 | R 21 Tarxien Rainbows FC 4 Senglea Athletic 2 M19:00 | 17/02/21 | R 16 Senglea Athletic 1 Lija Athletic 3 M20:00 | 13/02/21 | R 20 Senglea Athletic 0 Floriana FC 2 M20:00 | 06/02/21 | R 19 Sliema Wanderers 3 Senglea Athletic 1 |
