| 1 | |  Esperance Sportive de Tunis | 26 | 19 | 3 | 4 | 37 | 16 | 21 | 60 | M16:00 | 19/05/21 | R 26  Esperance Sportive de Tunis 1 ES Metlaoui 2 M15:30 | 09/05/21 | R 25 CA Bizertin 2 Esperance Sportive de Tunis 0 B15:30 | 05/05/21 | R 24 Club Africain 1 Esperance Sportive de Tunis 1 G15:30 | 01/05/21 | R 22 Stade Tunisien 0 Esperance Sportive de Tunis 1 B15:30 | 25/04/21 | R 21 Esperance Sportive de Tunis 0 Club Sportif Sfaxien 0 G15:30 | 18/04/21 | R 19 Esperance Sportive de Tunis 3 JS Kairouanaise 1 |
| 2 | |  Etoile Sportive du Sahel | 26 | 15 | 5 | 6 | 46 | 26 | 20 | 50 | B16:00 | 19/05/21 | R 26 Etoile Sportive du Sahel 4 Olypique De Beja 4 M15:30 | 09/05/21 | R 25 US Ben Guerdane 1 Etoile Sportive du Sahel 0 M15:30 | 05/05/21 | R 24 Stade Tunisien 1 Etoile Sportive du Sahel 0 G15:30 | 02/05/21 | R 22 AS Rejiche 0 Etoile Sportive du Sahel 1 G15:30 | 18/04/21 | R 19 Club Sportif Sfaxien 1 Etoile Sportive du Sahel 2 M15:30 | 14/04/21 | R 17 US Monastir 3 Etoile Sportive du Sahel 1 |
| 3 | |  US Ben Guerdane | 26 | 10 | 11 | 5 | 25 | 16 | 9 | 41 | M16:00 | 19/05/21 | R 26 US Ben Guerdane 0 CA Bizertin 1 G15:30 | 09/05/21 | R 25 US Ben Guerdane 1 Etoile Sportive du Sahel 0 B15:30 | 05/05/21 | R 24 Olypique De Beja 1 US Ben Guerdane 1 B15:00 | 07/04/21 | R 23 US Ben Guerdane 0 Stade Tunisien 0 G16:00 | 03/04/21 | R 22 JS Kairouanaise 1 US Ben Guerdane 3 B16:00 | 31/03/21 | R 21 US Ben Guerdane 1 US Tataouine 1 |
| 4 | |  Club Sportif Sfaxien | 26 | 10 | 10 | 6 | 29 | 16 | 13 | 40 | B16:00 | 19/05/21 | R 26 AS Rejiche 3 Club Sportif Sfaxien 3 G15:30 | 09/05/21 | R 25 Club Sportif Sfaxien 2 JS Kairouanaise 0 M15:30 | 05/05/21 | R 24 Club Sportif Sfaxien 0 AS Soliman 1 B15:30 | 02/05/21 | R 22 Club Sportif Sfaxien 0 CA Bizertin 0 B15:30 | 25/04/21 | R 21 Esperance Sportive de Tunis 0 Club Sportif Sfaxien 0 M15:30 | 18/04/21 | R 19 Club Sportif Sfaxien 1 Etoile Sportive du Sahel 2 |
| 5 | |  AS Soliman | 26 | 11 | 7 | 8 | 35 | 34 | 1 | 40 | B16:00 | 19/05/21 | R 26 US Monastir 2 AS Soliman 2 G15:30 | 09/05/21 | R 25 AS Soliman 2 AS Rejiche 1 G15:30 | 05/05/21 | R 24 Club Sportif Sfaxien 0 AS Soliman 1 G16:00 | 07/04/21 | R 23 AS Soliman 3 US Tataouine 1 M16:00 | 04/04/21 | R 22 Club Africain 2 AS Soliman 1 G16:00 | 31/03/21 | R 21 AS Soliman 2 JS Kairouanaise 1 |
| 6 | |  AS Rejiche | 26 | 9 | 9 | 8 | 27 | 23 | 4 | 36 | B16:00 | 19/05/21 | R 26 AS Rejiche 3 Club Sportif Sfaxien 3 M15:30 | 09/05/21 | R 25 AS Soliman 2 AS Rejiche 1 G15:30 | 05/05/21 | R 24 AS Rejiche 1 ES Metlaoui 0 M15:30 | 02/05/21 | R 22 AS Rejiche 0 Etoile Sportive du Sahel 1 B16:00 | 07/04/21 | R 23 CA Bizertin 1 AS Rejiche 1 G16:00 | 31/03/21 | R 21 US Monastir 2 AS Rejiche 3 |
| 7 | |  Club Africain | 26 | 7 | 12 | 7 | 26 | 30 | -4 | 33 | G16:00 | 19/05/21 | R 26 Stade Tunisien 0 Club Africain 1 B15:30 | 09/05/21 | R 25 Club Africain 1 Olypique De Beja 1 B15:30 | 05/05/21 | R 24 Club Africain 1 Esperance Sportive de Tunis 1 G16:00 | 07/04/21 | R 23 US Monastir 0 Club Africain 1 G16:00 | 04/04/21 | R 22 Club Africain 2 AS Soliman 1 B16:00 | 31/03/21 | R 21 Etoile Sportive du Sahel 2 Club Africain 2 |
| 8 | |  US Tataouine | 26 | 8 | 9 | 9 | 24 | 30 | -6 | 33 | G16:00 | 19/05/21 | R 26 JS Kairouanaise 0 US Tataouine 1 G15:30 | 09/05/21 | R 25 US Tataouine 2 Stade Tunisien 1 G15:30 | 05/05/21 | R 24 US Tataouine 3 US Monastir 1 M15:30 | 14/04/21 | R 16 US Tataouine 1 Esperance Sportive de Tunis 3 M16:00 | 07/04/21 | R 23 AS Soliman 3 US Tataouine 1 B16:00 | 04/04/21 | R 22 US Tataouine 0 ES Metlaoui 0 |
| 9 | |  ES Metlaoui | 26 | 8 | 8 | 10 | 17 | 21 | -4 | 32 | G16:00 | 19/05/21 | R 26 Esperance Sportive de Tunis 1 ES Metlaoui 2 G15:30 | 09/05/21 | R 25 ES Metlaoui 2 US Monastir 0 M15:30 | 05/05/21 | R 24 AS Rejiche 1 ES Metlaoui 0 M16:00 | 07/04/21 | R 23 ES Metlaoui 0 Club Sportif Sfaxien 1 B16:00 | 04/04/21 | R 22 US Tataouine 0 ES Metlaoui 0 G16:00 | 31/03/21 | R 21 ES Metlaoui 1 Stade Tunisien 0 |
| 10 | |  US Monastir | 26 | 8 | 7 | 11 | 28 | 29 | -1 | 31 | B16:00 | 19/05/21 | R 26 US Monastir 2 AS Soliman 2 M15:30 | 09/05/21 | R 25 ES Metlaoui 2 US Monastir 0 M15:30 | 05/05/21 | R 24 US Tataouine 3 US Monastir 1 G15:30 | 14/04/21 | R 17 US Monastir 3 Etoile Sportive du Sahel 1 M16:00 | 07/04/21 | R 23 US Monastir 0 Club Africain 1 M16:00 | 04/04/21 | R 22 Olypique De Beja 3 US Monastir 0 |
| 11 | |  Olypique De Beja | 26 | 7 | 10 | 9 | 25 | 26 | -1 | 31 | B16:00 | 19/05/21 | R 26 Etoile Sportive du Sahel 4 Olypique De Beja 4 B15:30 | 09/05/21 | R 25 Club Africain 1 Olypique De Beja 1 B15:30 | 05/05/21 | R 24 Olypique De Beja 1 US Ben Guerdane 1 B15:30 | 14/04/21 | R 17 Club Sportif Sfaxien 0 Olypique De Beja 0 M18:15 | 07/04/21 | R 23 Esperance Sportive de Tunis 1 Olypique De Beja 0 G16:00 | 04/04/21 | R 22 Olypique De Beja 3 US Monastir 0 |
| 12 | |  CA Bizertin | 26 | 8 | 7 | 11 | 21 | 27 | -6 | 31 | G16:00 | 19/05/21 | R 26 US Ben Guerdane 0 CA Bizertin 1 G15:30 | 09/05/21 | R 25 CA Bizertin 2 Esperance Sportive de Tunis 0 G15:30 | 05/05/21 | R 24 JS Kairouanaise 1 CA Bizertin 4 B15:30 | 02/05/21 | R 22 Club Sportif Sfaxien 0 CA Bizertin 0 B16:00 | 07/04/21 | R 23 CA Bizertin 1 AS Rejiche 1 G16:00 | 31/03/21 | R 21 CA Bizertin 1 Olypique De Beja 0 |
| 13 | |  Stade Tunisien | 26 | 6 | 11 | 9 | 22 | 22 | 0 | 29 | B17:00 | 06/10/21 | R 2 CO Medenine 0 Stade Tunisien 0 M16:00 | 02/10/21 | R 1 Stade Tunisien 0 ES Zarzis 1 M16:00 | 19/05/21 | R 26 Stade Tunisien 0 Club Africain 1 M15:30 | 09/05/21 | R 25 US Tataouine 2 Stade Tunisien 1 G15:30 | 05/05/21 | R 24 Stade Tunisien 1 Etoile Sportive du Sahel 0 M15:30 | 01/05/21 | R 22 Stade Tunisien 0 Esperance Sportive de Tunis 1 |
| 14 | |  JS Kairouanaise | 26 | 0 | 3 | 23 | 14 | 60 | -46 | 3 | M17:00 | 06/10/21 | R 2 ES Zarzis 2 JS Kairouanaise 0 G16:00 | 02/10/21 | R 1 JS Kairouanaise 2 CO Medenine 1 M16:00 | 19/05/21 | R 26 JS Kairouanaise 0 US Tataouine 1 M15:30 | 09/05/21 | R 25 Club Sportif Sfaxien 2 JS Kairouanaise 0 M15:30 | 05/05/21 | R 24 JS Kairouanaise 1 CA Bizertin 4 M15:30 | 18/04/21 | R 19 Esperance Sportive de Tunis 3 JS Kairouanaise 1 |
EGS Gafsa 
Club S Hammam-Lif 
EO Sidi Bouzid