| 1 | |  FC Sheriff Tiraspol | 28 | 22 | 4 | 2 | 75 | 8 | 67 | 70 | G17:00 | 14/05/22 | R 28  FC Sfintul Gheorghe 0 FC Sheriff Tiraspol 2 B17:00 | 07/05/22 | R 27 FC Milsami 1 FC Sheriff Tiraspol 1 G16:00 | 29/04/22 | R 26 FC Dinamo Auto 0 FC Sheriff Tiraspol 3 G00:00 | 21/04/22 | R 25 FC Sheriff Tiraspol 3 FC Floresti 0 B18:00 | 16/04/22 | R 24 FC Zimbru Chisinau 1 FC Sheriff Tiraspol 1 G18:00 | 08/04/22 | R 23 FC Sheriff Tiraspol 1 Petrocub Hincesti 0 |
| 2 | |  Petrocub Hincesti | 28 | 20 | 4 | 4 | 62 | 20 | 42 | 64 | G17:00 | 14/05/22 | R 28 FC Zimbru Chisinau 0 Petrocub Hincesti 3 G17:00 | 08/05/22 | R 27 Petrocub Hincesti 5 FC Dinamo Auto 0 G18:00 | 30/04/22 | R 26 Petrocub Hincesti 3 FC Balti 2 G16:00 | 22/04/22 | R 25 FC Sfintul Gheorghe 0 Petrocub Hincesti 4 G18:00 | 17/04/22 | R 24 Petrocub Hincesti 1 FC Milsami 0 M18:00 | 08/04/22 | R 23 FC Sheriff Tiraspol 1 Petrocub Hincesti 0 |
| 3 | |  FC Milsami | 28 | 15 | 6 | 7 | 50 | 31 | 19 | 51 | B17:00 | 14/05/22 | R 28 FC Dinamo Auto 2 FC Milsami 2 B17:00 | 07/05/22 | R 27 FC Milsami 1 FC Sheriff Tiraspol 1 G00:00 | 29/04/22 | R 26 FC Floresti 0 FC Milsami 3 G16:00 | 21/04/22 | R 25 FC Milsami 3 FC Zimbru Chisinau 0 M18:00 | 17/04/22 | R 24 Petrocub Hincesti 1 FC Milsami 0 M16:00 | 09/04/22 | R 23 FC Milsami 0 FC Balti 2 |
| 4 | |  FC Sfintul Gheorghe | 28 | 10 | 8 | 10 | 38 | 39 | -1 | 38 | M17:00 | 14/05/22 | R 28 FC Sfintul Gheorghe 0 FC Sheriff Tiraspol 2 G18:00 | 07/05/22 | R 27 FC Sfintul Gheorghe 3 FC Floresti 0 M16:00 | 30/04/22 | R 26 FC Sfintul Gheorghe 0 FC Zimbru Chisinau 1 M16:00 | 22/04/22 | R 25 FC Sfintul Gheorghe 0 Petrocub Hincesti 4 B16:00 | 17/04/22 | R 24 FC Balti 0 FC Sfintul Gheorghe 0 G16:00 | 08/04/22 | R 23 FC Sfintul Gheorghe 4 FC Dinamo Auto 0 |
| 5 | |  FC Balti | 28 | 11 | 3 | 14 | 39 | 39 | 0 | 36 | G18:00 | 14/05/22 | R 28 FC Floresti 0 FC Balti 3 G19:00 | 08/05/22 | R 27 FC Balti 1 FC Zimbru Chisinau 0 M18:00 | 30/04/22 | R 26 Petrocub Hincesti 3 FC Balti 2 G18:00 | 22/04/22 | R 25 FC Balti 3 FC Dinamo Auto 0 B16:00 | 17/04/22 | R 24 FC Balti 0 FC Sfintul Gheorghe 0 G16:00 | 09/04/22 | R 23 FC Milsami 0 FC Balti 2 |
| 6 | |  FC Dinamo Auto | 28 | 9 | 5 | 14 | 35 | 72 | -37 | 32 | B17:00 | 14/05/22 | R 28 FC Dinamo Auto 2 FC Milsami 2 M17:00 | 08/05/22 | R 27 Petrocub Hincesti 5 FC Dinamo Auto 0 M16:00 | 29/04/22 | R 26 FC Dinamo Auto 0 FC Sheriff Tiraspol 3 M18:00 | 22/04/22 | R 25 FC Balti 3 FC Dinamo Auto 0 G00:00 | 16/04/22 | R 24 FC Dinamo Auto 3 FC Floresti 0 M16:00 | 08/04/22 | R 23 FC Sfintul Gheorghe 4 FC Dinamo Auto 0 |
| 7 | |  FC Zimbru Chisinau | 28 | 7 | 6 | 15 | 32 | 46 | -14 | 27 | M17:00 | 14/05/22 | R 28 FC Zimbru Chisinau 0 Petrocub Hincesti 3 M19:00 | 08/05/22 | R 27 FC Balti 1 FC Zimbru Chisinau 0 G16:00 | 30/04/22 | R 26 FC Sfintul Gheorghe 0 FC Zimbru Chisinau 1 M16:00 | 21/04/22 | R 25 FC Milsami 3 FC Zimbru Chisinau 0 B18:00 | 16/04/22 | R 24 FC Zimbru Chisinau 1 FC Sheriff Tiraspol 1 |
| 8 | |  FC Floresti | 28 | 0 | 0 | 28 | 12 | 88 | -76 | -6 | M18:00 | 14/05/22 | R 28 FC Floresti 0 FC Balti 3 M18:00 | 07/05/22 | R 27 FC Sfintul Gheorghe 3 FC Floresti 0 M00:00 | 29/04/22 | R 26 FC Floresti 0 FC Milsami 3 M00:00 | 21/04/22 | R 25 FC Sheriff Tiraspol 3 FC Floresti 0 M00:00 | 16/04/22 | R 24 FC Dinamo Auto 3 FC Floresti 0 M00:00 | 09/04/22 | R 23 FC Floresti 0 FC Zimbru Chisinau 3 |
