| 1 | |  Llantwit Major | 29 | 23 | 2 | 4 | 68 | 31 | 37 | 71 | G16:30 | 30/04/22 | R 30  Cwmbran Celtic 0 Llantwit Major 5 G16:30 | 18/04/22 | R 20 Undy Athletic 1 Llantwit Major 3 G16:30 | 15/04/22 | R 19 Llantwit Major 2 Undy Athletic 0 G16:30 | 09/04/22 | R 29 Llantwit Major 2 Cambrian & Clydach Vale 1 G20:00 | 06/04/22 | R 28 Goytre Utd. 2 Llantwit Major 4 G21:30 | 01/04/22 | R 26 Afan Lido 0 Llantwit Major 1 |
| 2 | |  Pontypridd Town | 29 | 20 | 6 | 3 | 77 | 30 | 47 | 66 | G16:30 | 30/04/22 | R 30 Carmarthen Town 0 Pontypridd Town 2 G16:30 | 18/04/22 | R 20 Pontypridd Town 2 Cambrian & Clydach Vale 1 G16:30 | 15/04/22 | R 19 Cambrian & Clydach Vale 1 Pontypridd Town 2 G21:45 | 08/04/22 | R 29 Pontypridd Town 2 Trefelin BGC 1 G16:30 | 02/04/22 | R 26 Pontypridd Town 4 Llanelli Town 1 G22:30 | 25/03/22 | R 27 Risca United 0 Pontypridd Town 1 |
| 3 | |  Briton Ferry Llansawel | 29 | 16 | 5 | 8 | 73 | 35 | 38 | 53 | G16:30 | 30/04/22 | R 30 Swansea University 1 Briton Ferry Llansawel 3 G16:30 | 18/04/22 | R 20 Llanelli Town 0 Briton Ferry Llansawel 4 M14:00 | 15/04/22 | R 19 Briton Ferry Llansawel 0 Llanelli Town 1 G21:30 | 08/04/22 | R 29 Briton Ferry Llansawel 2 Port Talbot Town 1 M21:30 | 01/04/22 | R 26 Goytre Utd. 3 Briton Ferry Llansawel 1 G22:45 | 25/03/22 | R 27 Briton Ferry Llansawel 3 Cambrian & Clydach Vale 2 |
| 4 | |  Carmarthen Town | 29 | 15 | 9 | 5 | 52 | 23 | 29 | 51 | M16:30 | 30/04/22 | R 30 Carmarthen Town 0 Pontypridd Town 2 G16:30 | 18/04/22 | R 20 Carmarthen Town 4 Ammanford 0 G21:30 | 15/04/22 | R 19 Ammanford 1 Carmarthen Town 3 B16:30 | 09/04/22 | R 29 Risca United 1 Carmarthen Town 1 G16:30 | 02/04/22 | R 26 Carmarthen Town 4 Undy Athletic 0 M17:30 | 26/03/22 | R 27 Taffs Well 2 Carmarthen Town 0 |
| 5 | |  Goytre Utd. | 29 | 15 | 6 | 8 | 55 | 34 | 21 | 51 | M16:30 | 30/04/22 | R 30 Goytre Utd. 0 Taffs Well 2 B14:00 | 18/04/22 | R 20 Trefelin BGC 1 Goytre Utd. 1 M16:30 | 15/04/22 | R 19 Goytre Utd. 1 Trefelin BGC 2 B16:30 | 09/04/22 | R 29 Undy Athletic 1 Goytre Utd. 1 M20:00 | 06/04/22 | R 28 Goytre Utd. 2 Llantwit Major 4 G21:30 | 01/04/22 | R 26 Goytre Utd. 3 Briton Ferry Llansawel 1 |
| 6 | |  Cambrian & Clydach Vale | 29 | 14 | 6 | 9 | 70 | 42 | 28 | 48 | G16:30 | 30/04/22 | R 30 Cambrian & Clydach Vale 3 Undy Athletic 0 M16:30 | 18/04/22 | R 20 Pontypridd Town 2 Cambrian & Clydach Vale 1 M16:30 | 15/04/22 | R 19 Cambrian & Clydach Vale 1 Pontypridd Town 2 M16:30 | 09/04/22 | R 29 Llantwit Major 2 Cambrian & Clydach Vale 1 G16:30 | 02/04/22 | R 26 Cambrian & Clydach Vale 4 Cwmbran Celtic 1 M22:45 | 25/03/22 | R 27 Briton Ferry Llansawel 3 Cambrian & Clydach Vale 2 |
| 7 | |  Taffs Well | 29 | 13 | 7 | 9 | 55 | 47 | 8 | 46 | G16:30 | 30/04/22 | R 30 Goytre Utd. 0 Taffs Well 2 G16:30 | 18/04/22 | R 20 Taffs Well 4 Swansea University 2 G16:30 | 15/04/22 | R 19 Swansea University 1 Taffs Well 2 M21:30 | 08/04/22 | R 29 Taffs Well 0 Ammanford 1 B16:30 | 02/04/22 | R 26 Trefelin BGC 0 Taffs Well 0 G17:30 | 26/03/22 | R 27 Taffs Well 2 Carmarthen Town 0 |
| 8 | |  Swansea University | 29 | 11 | 7 | 11 | 43 | 40 | 3 | 40 | M16:30 | 30/04/22 | R 30 Swansea University 1 Briton Ferry Llansawel 3 M16:30 | 18/04/22 | R 20 Taffs Well 4 Swansea University 2 M16:30 | 15/04/22 | R 19 Swansea University 1 Taffs Well 2 G16:30 | 09/04/22 | R 29 Swansea University 3 Cwmbran Celtic 1 B21:30 | 01/04/22 | R 26 Ammanford 0 Swansea University 0 M17:30 | 26/03/22 | R 27 Swansea University 0 Goytre Utd. 1 |
| 9 | |  Llanelli Town | 29 | 11 | 7 | 11 | 43 | 49 | -6 | 40 | M16:30 | 30/04/22 | R 30 Ammanford 5 Llanelli Town 0 M16:30 | 18/04/22 | R 20 Llanelli Town 0 Briton Ferry Llansawel 4 G14:00 | 15/04/22 | R 19 Briton Ferry Llansawel 0 Llanelli Town 1 M16:30 | 02/04/22 | R 26 Pontypridd Town 4 Llanelli Town 1 G17:00 | 26/03/22 | R 27 Trefelin BGC 0 Llanelli Town 1 B22:30 | 18/03/22 | R 29 Llanelli Town 1 Afan Lido 1 |
| 10 | |  Afan Lido | 29 | 11 | 3 | 15 | 43 | 66 | -23 | 36 | G16:30 | 30/04/22 | R 30 Afan Lido 2 Risca United 1 G16:00 | 18/04/22 | R 20 Port Talbot Town 0 Afan Lido 2 G19:30 | 15/04/22 | R 19 Afan Lido 2 Port Talbot Town 0 M21:30 | 01/04/22 | R 26 Afan Lido 0 Llantwit Major 1 G17:00 | 26/03/22 | R 27 Undy Athletic 0 Afan Lido 2 B22:30 | 18/03/22 | R 29 Llanelli Town 1 Afan Lido 1 |
| 11 | |  Trefelin BGC | 29 | 8 | 10 | 11 | 54 | 51 | 3 | 34 | G16:30 | 30/04/22 | R 30 Trefelin BGC 4 Port Talbot Town 0 B14:00 | 18/04/22 | R 20 Trefelin BGC 1 Goytre Utd. 1 G16:30 | 15/04/22 | R 19 Goytre Utd. 1 Trefelin BGC 2 M21:45 | 08/04/22 | R 29 Pontypridd Town 2 Trefelin BGC 1 B16:30 | 02/04/22 | R 26 Trefelin BGC 0 Taffs Well 0 M17:00 | 26/03/22 | R 27 Trefelin BGC 0 Llanelli Town 1 |
| 12 | |  Cwmbran Celtic | 29 | 10 | 4 | 15 | 43 | 69 | -26 | 34 | M16:30 | 30/04/22 | R 30 Cwmbran Celtic 0 Llantwit Major 5 B16:30 | 18/04/22 | R 20 Cwmbran Celtic 3 Risca United 3 B16:30 | 15/04/22 | R 20 Risca United 1 Cwmbran Celtic 1 M16:30 | 09/04/22 | R 29 Swansea University 3 Cwmbran Celtic 1 M16:30 | 02/04/22 | R 26 Cambrian & Clydach Vale 4 Cwmbran Celtic 1 G17:00 | 26/03/22 | R 27 Cwmbran Celtic 2 Port Talbot Town 1 |
| 13 | |  Ammanford | 29 | 9 | 4 | 16 | 53 | 56 | -3 | 31 | G16:30 | 30/04/22 | R 30 Ammanford 5 Llanelli Town 0 M16:30 | 18/04/22 | R 20 Carmarthen Town 4 Ammanford 0 M21:30 | 15/04/22 | R 19 Ammanford 1 Carmarthen Town 3 G21:30 | 08/04/22 | R 29 Taffs Well 0 Ammanford 1 B21:30 | 01/04/22 | R 26 Ammanford 0 Swansea University 0 B17:30 | 26/03/22 | R 27 Llantwit Major 1 Ammanford 1 |
| 14 | |  Risca United | 29 | 7 | 10 | 12 | 42 | 49 | -7 | 31 | M16:30 | 30/04/22 | R 30 Afan Lido 2 Risca United 1 B16:30 | 18/04/22 | R 20 Cwmbran Celtic 3 Risca United 3 B16:30 | 15/04/22 | R 20 Risca United 1 Cwmbran Celtic 1 B16:30 | 09/04/22 | R 29 Risca United 1 Carmarthen Town 1 G16:30 | 02/04/22 | R 26 Port Talbot Town 0 Risca United 1 M22:30 | 25/03/22 | R 27 Risca United 0 Pontypridd Town 1 |
| 15 | |  Undy Athletic | 29 | 5 | 2 | 22 | 41 | 81 | -40 | 17 | M16:30 | 30/04/22 | R 30 Cambrian & Clydach Vale 3 Undy Athletic 0 M16:30 | 18/04/22 | R 20 Undy Athletic 1 Llantwit Major 3 M16:30 | 15/04/22 | R 19 Llantwit Major 2 Undy Athletic 0 B16:30 | 09/04/22 | R 29 Undy Athletic 1 Goytre Utd. 1 M16:30 | 02/04/22 | R 26 Carmarthen Town 4 Undy Athletic 0 M17:00 | 26/03/22 | R 27 Undy Athletic 0 Afan Lido 2 |
| 16 | |  Port Talbot Town | 29 | 0 | 0 | 29 | 8 | 117 | -109 | 0 | M16:30 | 30/04/22 | R 30 Trefelin BGC 4 Port Talbot Town 0 M16:00 | 18/04/22 | R 20 Port Talbot Town 0 Afan Lido 2 M19:30 | 15/04/22 | R 19 Afan Lido 2 Port Talbot Town 0 M21:30 | 08/04/22 | R 29 Briton Ferry Llansawel 2 Port Talbot Town 1 M16:30 | 02/04/22 | R 26 Port Talbot Town 0 Risca United 1 M17:00 | 26/03/22 | R 27 Cwmbran Celtic 2 Port Talbot Town 1 |
