| 1 | |  Adelaide Comets FC | 22 | 12 | 7 | 3 | 40 | 26 | 14 | 43 | G13:00 | 18/09/21 | R 22  Adelaide Comets FC 3 Adelaide Olympic FC 2 G08:00 | 11/09/21 | R 21 Adelaide United FC 1 Adelaide Comets FC 2 G08:30 | 04/09/21 | R 20 Adelaide Comets FC 4 Sturt Lions 0 |
| 2 | |  Adelaide City FC | 22 | 11 | 8 | 3 | 40 | 20 | 20 | 41 | B13:00 | 18/09/21 | R 22 Croydon Kings FC 1 Adelaide City FC 1 B08:30 | 11/09/21 | R 21 Adelaide City FC 0 South Adelaide FC 0 B08:30 | 04/09/21 | R 20 Cumberland United 2 Adelaide City FC 2 G13:00 | 01/09/21 | R 15 Adelaide City FC 2 Sturt Lions 0 |
| 3 | |  Campbelltown City SC | 22 | 10 | 5 | 7 | 41 | 28 | 13 | 35 | G13:00 | 18/09/21 | R 22 Campbelltown City SC 4 Adelaide Blue Eagles 0 B13:00 | 14/09/21 | R 15 Campbelltown City SC 0 Adelaide Olympic FC 0 G12:30 | 10/09/21 | R 21 Adelaide Croatia Raiders SC 2 Campbelltown City SC 3 M13:00 | 07/09/21 | R 13 Campbelltown City SC 0 Sturt Lions 1 M13:45 | 03/09/21 | R 20 Croydon Kings FC 1 Campbelltown City SC 0 |
| 4 | |  North Eastern Metrostars SC | 22 | 9 | 6 | 7 | 36 | 26 | 10 | 33 | M13:00 | 18/09/21 | R 22 North Eastern Metrostars SC 0 Adelaide Croatia Raiders SC 1 B11:30 | 11/09/21 | R 21 Adelaide Olympic FC 1 North Eastern Metrostars SC 1 G13:45 | 07/09/21 | R 15 Croydon Kings FC 1 North Eastern Metrostars SC 3 M08:30 | 04/09/21 | R 20 North Eastern Metrostars SC 2 Adelaide United FC 3 B08:30 | 28/08/21 | R 19 Sturt Lions 2 North Eastern Metrostars SC 2 |
| 5 | |  Sturt Lions | 22 | 9 | 6 | 7 | 34 | 34 | 0 | 33 | M13:00 | 18/09/21 | R 22 South Adelaide FC 5 Sturt Lions 2 G08:30 | 11/09/21 | R 21 Sturt Lions 4 Cumberland United 0 G13:00 | 07/09/21 | R 13 Campbelltown City SC 0 Sturt Lions 1 |
| 6 | |  South Adelaide FC | 22 | 9 | 5 | 8 | 38 | 36 | 2 | 32 | G13:00 | 18/09/21 | R 22 South Adelaide FC 5 Sturt Lions 2 B08:30 | 11/09/21 | R 21 Adelaide City FC 0 South Adelaide FC 0 G08:30 | 04/09/21 | R 20 South Adelaide FC 3 Adelaide Blue Eagles 2 B13:00 | 01/09/21 | R 15 South Adelaide FC 1 Adelaide Comets FC 1 |
| 7 | |  Adelaide Olympic FC | 22 | 6 | 11 | 5 | 37 | 33 | 4 | 29 | M13:00 | 18/09/21 | R 22 Adelaide Comets FC 3 Adelaide Olympic FC 2 B13:00 | 14/09/21 | R 15 Campbelltown City SC 0 Adelaide Olympic FC 0 B11:30 | 11/09/21 | R 21 Adelaide Olympic FC 1 North Eastern Metrostars SC 1 G11:30 | 04/09/21 | R 20 Adelaide Olympic FC 2 Adelaide Croatia Raiders SC 0 B08:00 | 28/08/21 | R 19 Adelaide United FC 1 Adelaide Olympic FC 1 B11:30 | 21/08/21 | R 18 Adelaide Olympic FC 2 Sturt Lions 2 |
| 8 | |  Croydon Kings FC | 22 | 7 | 8 | 7 | 29 | 30 | -1 | 29 | B13:00 | 18/09/21 | R 22 Croydon Kings FC 1 Adelaide City FC 1 G08:30 | 11/09/21 | R 21 Adelaide Blue Eagles 2 Croydon Kings FC 4 M13:45 | 07/09/21 | R 15 Croydon Kings FC 1 North Eastern Metrostars SC 3 G13:45 | 03/09/21 | R 20 Croydon Kings FC 1 Campbelltown City SC 0 G12:30 | 28/08/21 | R 19 Adelaide Croatia Raiders SC 0 Croydon Kings FC 2 G08:30 | 21/08/21 | R 18 South Adelaide FC 1 Croydon Kings FC 2 |
| 9 | |  Adelaide United FC | 22 | 7 | 4 | 11 | 34 | 45 | -11 | 25 | M13:00 | 18/09/21 | R 22 Cumberland United 4 Adelaide United FC 0 M08:00 | 11/09/21 | R 21 Adelaide United FC 1 Adelaide Comets FC 2 G08:30 | 04/09/21 | R 20 North Eastern Metrostars SC 2 Adelaide United FC 3 M15:15 | 31/08/21 | R 15 Adelaide Blue Eagles 4 Adelaide United FC 2 B08:00 | 28/08/21 | R 19 Adelaide United FC 1 Adelaide Olympic FC 1 M13:45 | 20/08/21 | R 18 Adelaide United FC 2 Adelaide Croatia Raiders SC 3 |
| 10 | |  Cumberland United | 22 | 7 | 4 | 11 | 28 | 45 | -17 | 25 | G13:00 | 18/09/21 | R 22 Cumberland United 4 Adelaide United FC 0 M08:30 | 11/09/21 | R 21 Sturt Lions 4 Cumberland United 0 B08:30 | 04/09/21 | R 20 Cumberland United 2 Adelaide City FC 2 G12:30 | 31/08/21 | R 15 Adelaide Croatia Raiders SC 1 Cumberland United 2 M08:30 | 28/08/21 | R 19 Adelaide Blue Eagles 2 Cumberland United 1 B08:30 | 21/08/21 | R 18 Cumberland United 1 Campbelltown City SC 1 |
| 11 | |  Adelaide Croatia Raiders SC | 22 | 6 | 4 | 12 | 33 | 48 | -15 | 22 | G13:00 | 18/09/21 | R 22 North Eastern Metrostars SC 0 Adelaide Croatia Raiders SC 1 M12:30 | 10/09/21 | R 21 Adelaide Croatia Raiders SC 2 Campbelltown City SC 3 M11:30 | 04/09/21 | R 20 Adelaide Olympic FC 2 Adelaide Croatia Raiders SC 0 M12:30 | 31/08/21 | R 15 Adelaide Croatia Raiders SC 1 Cumberland United 2 M12:30 | 28/08/21 | R 19 Adelaide Croatia Raiders SC 0 Croydon Kings FC 2 G13:45 | 20/08/21 | R 18 Adelaide United FC 2 Adelaide Croatia Raiders SC 3 |
| 12 | |  Adelaide Blue Eagles | 22 | 3 | 4 | 15 | 27 | 46 | -19 | 13 | M13:00 | 18/09/21 | R 22 Campbelltown City SC 4 Adelaide Blue Eagles 0 M08:30 | 11/09/21 | R 21 Adelaide Blue Eagles 2 Croydon Kings FC 4 M08:30 | 04/09/21 | R 20 South Adelaide FC 3 Adelaide Blue Eagles 2 G15:15 | 31/08/21 | R 15 Adelaide Blue Eagles 4 Adelaide United FC 2 G08:30 | 28/08/21 | R 19 Adelaide Blue Eagles 2 Cumberland United 1 M08:30 | 21/08/21 | R 18 Adelaide Comets FC 2 Adelaide Blue Eagles 1 |
