| 1 | |  Derry City | 33 | 20 | 9 | 4 | 65 | 24 | 41 | 69 | G21:45 | 30/10/10 | R 33  Monaghan United FC 0 Derry City 1 B21:45 | 22/10/10 | R 32 Derry City 2 Finn Harps 2 G21:00 | 16/10/10 | R 31 Salthill Devon 1 Derry City 5 G20:00 | 09/10/10 | R 30 Derry City 3 Shelbourne FC 0 B22:00 | 01/10/10 | R 29 Wexford 1 Derry City 1 G21:45 | 24/09/10 | R 28 Derry City 6 Mervue United 0 |
| 2 | |  Waterford FC | 33 | 20 | 6 | 7 | 59 | 27 | 32 | 66 | G21:45 | 30/10/10 | R 33 Shelbourne FC 1 Waterford FC 2 G21:45 | 22/10/10 | R 32 Waterford FC 3 Athlone Town 2 G22:00 | 15/10/10 | R 31 Longford Town 0 Waterford FC 2 G21:00 | 09/10/10 | R 30 Waterford FC 3 Finn Harps 1 M22:00 | 01/10/10 | R 29 Monaghan United FC 4 Waterford FC 2 G21:45 | 24/09/10 | R 28 Waterford FC 3 Limeric 0 |
| 3 | |  Monaghan United FC | 33 | 18 | 8 | 7 | 59 | 29 | 30 | 62 | M21:45 | 30/10/10 | R 33 Monaghan United FC 0 Derry City 1 M21:00 | 23/10/10 | R 32 Mervue United 2 Monaghan United FC 1 B22:00 | 15/10/10 | R 31 Monaghan United FC 0 Limeric 0 G21:45 | 11/10/10 | R 28 Salthill Devon 0 Monaghan United FC 3 M17:00 | 09/10/10 | R 30 Cork City FC 1 Monaghan United FC 0 G22:00 | 01/10/10 | R 29 Monaghan United FC 4 Waterford FC 2 |
| 4 | |  Shelbourne FC | 33 | 18 | 7 | 8 | 57 | 31 | 26 | 61 | M21:45 | 30/10/10 | R 33 Shelbourne FC 1 Waterford FC 2 G21:45 | 22/10/10 | R 32 Limeric 0 Shelbourne FC 1 G22:00 | 15/10/10 | R 31 Shelbourne FC 3 Mervue United 0 M20:00 | 09/10/10 | R 30 Derry City 3 Shelbourne FC 0 G22:00 | 01/10/10 | R 29 Shelbourne FC 2 Cork City FC 0 G21:30 | 25/09/10 | R 28 Athlone Town 0 Shelbourne FC 2 |
| 5 | |  Limeric | 33 | 17 | 6 | 10 | 55 | 35 | 20 | 57 | G21:45 | 30/10/10 | R 33 Athlone Town 1 Limeric 5 M21:45 | 22/10/10 | R 32 Limeric 0 Shelbourne FC 1 B22:00 | 15/10/10 | R 31 Monaghan United FC 0 Limeric 0 G21:45 | 07/10/10 | R 30 Limeric 1 Wexford 0 G21:00 | 02/10/10 | R 29 Salthill Devon 1 Limeric 3 M21:45 | 24/09/10 | R 28 Waterford FC 3 Limeric 0 |
| 6 | |  Cork City FC | 33 | 15 | 7 | 11 | 39 | 31 | 8 | 52 | M21:45 | 30/10/10 | R 33 Wexford 2 Cork City FC 1 M21:45 | 22/10/10 | R 32 Cork City FC 1 Salthill Devon 2 M22:00 | 15/10/10 | R 31 Finn Harps 1 Cork City FC 0 G17:00 | 09/10/10 | R 30 Cork City FC 1 Monaghan United FC 0 M22:00 | 01/10/10 | R 29 Shelbourne FC 2 Cork City FC 0 G21:45 | 24/09/10 | R 28 Cork City FC 1 Longford Town 0 |
| 7 | |  Wexford | 33 | 12 | 6 | 15 | 42 | 54 | -12 | 42 | G21:45 | 30/10/10 | R 33 Wexford 2 Cork City FC 1 G22:00 | 22/10/10 | R 32 Longford Town 1 Wexford 2 M22:00 | 15/10/10 | R 31 Wexford 1 Athlone Town 3 M21:45 | 07/10/10 | R 30 Limeric 1 Wexford 0 B22:00 | 01/10/10 | R 29 Wexford 1 Derry City 1 B22:00 | 24/09/10 | R 28 Finn Harps 1 Wexford 1 |
| 8 | |  Finn Harps | 33 | 10 | 10 | 13 | 37 | 43 | -6 | 40 | G21:45 | 30/10/10 | R 33 Finn Harps 4 Mervue United 0 B21:45 | 22/10/10 | R 32 Derry City 2 Finn Harps 2 G22:00 | 15/10/10 | R 31 Finn Harps 1 Cork City FC 0 M21:00 | 09/10/10 | R 30 Waterford FC 3 Finn Harps 1 B22:00 | 01/10/10 | R 29 Finn Harps 2 Athlone Town 2 B22:00 | 24/09/10 | R 28 Finn Harps 1 Wexford 1 |
| 9 | |  Longford Town | 33 | 9 | 8 | 16 | 39 | 53 | -14 | 35 | G21:45 | 30/10/10 | R 33 Salthill Devon 1 Longford Town 4 M22:00 | 22/10/10 | R 32 Longford Town 1 Wexford 2 M22:00 | 15/10/10 | R 31 Longford Town 0 Waterford FC 2 B21:30 | 09/10/10 | R 30 Athlone Town 0 Longford Town 0 B21:30 | 02/10/10 | R 29 Longford Town 2 Mervue United 2 M21:45 | 24/09/10 | R 28 Cork City FC 1 Longford Town 0 |
| 10 | |  Athlone Town | 33 | 6 | 13 | 14 | 35 | 50 | -15 | 31 | M21:45 | 30/10/10 | R 33 Athlone Town 1 Limeric 5 M21:45 | 22/10/10 | R 32 Waterford FC 3 Athlone Town 2 G22:00 | 15/10/10 | R 31 Wexford 1 Athlone Town 3 B21:30 | 09/10/10 | R 30 Athlone Town 0 Longford Town 0 B22:00 | 01/10/10 | R 29 Finn Harps 2 Athlone Town 2 M21:30 | 25/09/10 | R 28 Athlone Town 0 Shelbourne FC 2 |
| 11 | |  Mervue United | 33 | 5 | 4 | 24 | 34 | 84 | -50 | 19 | M21:45 | 30/10/10 | R 33 Finn Harps 4 Mervue United 0 G21:00 | 23/10/10 | R 32 Mervue United 2 Monaghan United FC 1 M22:00 | 15/10/10 | R 31 Shelbourne FC 3 Mervue United 0 G21:45 | 07/10/10 | R 30 Mervue United 2 Salthill Devon 1 B21:30 | 02/10/10 | R 29 Longford Town 2 Mervue United 2 M21:45 | 24/09/10 | R 28 Derry City 6 Mervue United 0 |
| 12 | |  Salthill Devon | 33 | 3 | 6 | 24 | 26 | 86 | -60 | 15 | M21:45 | 30/10/10 | R 33 Salthill Devon 1 Longford Town 4 G21:45 | 22/10/10 | R 32 Cork City FC 1 Salthill Devon 2 M21:00 | 16/10/10 | R 31 Salthill Devon 1 Derry City 5 M21:45 | 11/10/10 | R 28 Salthill Devon 0 Monaghan United FC 3 |
