| 1 | |  VfL Bochum | 34 | 21 | 4 | 9 | 66 | 39 | 27 | 67 | G16:30 | 23/05/21 | R 34  VfL Bochum 3 Sandhausen 1 B16:30 | 16/05/21 | R 33 Nürnberg 1 VfL Bochum 1 G14:30 | 09/05/21 | R 32 VfL Bochum 5 Jahn Regensburg 1 M21:30 | 26/04/21 | R 31 SV Darmstadt 1898 3 VfL Bochum 1 G19:30 | 21/04/21 | R 30 1. FC Heidenheim 1846 0 VfL Bochum 2 G14:30 | 18/04/21 | R 29 VfL Bochum 4 Hannover 96 3 |
| 2 | |  Greuther Furth | 34 | 18 | 10 | 6 | 69 | 44 | 25 | 64 | G16:30 | 23/05/21 | R 34 Greuther Furth 3 Fortuna Düsseldorf 2 G16:30 | 16/05/21 | R 33 SC Paderborn 2 Greuther Furth 4 B14:00 | 08/05/21 | R 32 Greuther Furth 2 Karlsruher SC 2 G19:30 | 28/04/21 | R 28 Greuther Furth 3 Sandhausen 2 M14:30 | 25/04/21 | R 31 Saint Pauli 2 Greuther Furth 1 G19:30 | 20/04/21 | R 30 Greuther Furth 3 E. Braunschweig 0 |
| 3 | |  Holstein Kiel | 34 | 18 | 8 | 8 | 57 | 35 | 22 | 62 | M16:30 | 23/05/21 | R 34 Holstein Kiel 2 SV Darmstadt 1898 3 M16:30 | 16/05/21 | R 33 Karlsruher SC 3 Holstein Kiel 2 G16:30 | 13/05/21 | R 28 Holstein Kiel 3 Jahn Regensburg 2 G19:00 | 10/05/21 | R 26 Holstein Kiel 1 Hannover 96 0 G19:30 | 07/05/21 | R 32 Holstein Kiel 4 Saint Pauli 0 G19:30 | 04/05/21 | R 30 Holstein Kiel 2 Sandhausen 0 |
| 4 | |  Hamburger SV | 34 | 16 | 10 | 8 | 71 | 44 | 27 | 58 | G16:30 | 23/05/21 | R 34 Hamburger SV 4 E. Braunschweig 0 M16:30 | 16/05/21 | R 33 VfL 1899 Osnabruck 3 Hamburger SV 2 G21:30 | 10/05/21 | R 32 Hamburger SV 5 Nürnberg 2 B19:30 | 29/04/21 | R 30 Hamburger SV 1 Karlsruher SC 1 B14:30 | 25/04/21 | R 31 Jahn Regensburg 1 Hamburger SV 1 M21:30 | 22/04/21 | R 29 Sandhausen 2 Hamburger SV 1 |
| 5 | |  Fortuna Düsseldorf | 34 | 16 | 8 | 10 | 55 | 46 | 9 | 56 | M16:30 | 23/05/21 | R 34 Greuther Furth 3 Fortuna Düsseldorf 2 G16:30 | 16/05/21 | R 33 Fortuna Düsseldorf 3 Erzgebirge Aue 0 B14:00 | 08/05/21 | R 32 Fortuna Düsseldorf 2 E. Braunschweig 2 G21:30 | 03/05/21 | R 28 Fortuna Düsseldorf 3 Karlsruher SC 2 M14:00 | 24/04/21 | R 31 SC Paderborn 2 Fortuna Düsseldorf 1 G19:30 | 21/04/21 | R 30 Fortuna Düsseldorf 2 Saint Pauli 0 |
| 6 | |  Karlsruher SC | 34 | 14 | 10 | 10 | 51 | 44 | 7 | 52 | G16:30 | 23/05/21 | R 34 1. FC Heidenheim 1846 1 Karlsruher SC 2 G16:30 | 16/05/21 | R 33 Karlsruher SC 3 Holstein Kiel 2 B14:00 | 08/05/21 | R 32 Greuther Furth 2 Karlsruher SC 2 M21:30 | 03/05/21 | R 28 Fortuna Düsseldorf 3 Karlsruher SC 2 B19:30 | 29/04/21 | R 30 Hamburger SV 1 Karlsruher SC 1 B19:00 | 26/04/21 | R 29 Karlsruher SC 0 Erzgebirge Aue 0 |
| 7 | |  SV Darmstadt 1898 | 34 | 15 | 6 | 13 | 63 | 55 | 8 | 51 | G16:30 | 23/05/21 | R 34 Holstein Kiel 2 SV Darmstadt 1898 3 G16:30 | 16/05/21 | R 33 SV Darmstadt 1898 5 1. FC Heidenheim 1846 1 G19:30 | 07/05/21 | R 32 Hannover 96 1 SV Darmstadt 1898 2 G21:30 | 26/04/21 | R 31 SV Darmstadt 1898 3 VfL Bochum 1 G19:30 | 20/04/21 | R 30 Kickers Würzburg 1 SV Darmstadt 1898 3 B19:30 | 16/04/21 | R 29 SV Darmstadt 1898 2 Greuther Furth 2 |
| 8 | |  1. FC Heidenheim 1846 | 34 | 15 | 6 | 13 | 49 | 49 | 0 | 51 | M16:30 | 23/05/21 | R 34 1. FC Heidenheim 1846 1 Karlsruher SC 2 M16:30 | 16/05/21 | R 33 SV Darmstadt 1898 5 1. FC Heidenheim 1846 1 G14:30 | 09/05/21 | R 32 1. FC Heidenheim 1846 2 Sandhausen 1 M14:00 | 24/04/21 | R 31 Nürnberg 3 1. FC Heidenheim 1846 1 M19:30 | 21/04/21 | R 30 1. FC Heidenheim 1846 0 VfL Bochum 2 G14:30 | 18/04/21 | R 29 Jahn Regensburg 0 1. FC Heidenheim 1846 3 |
| 9 | |  SC Paderborn | 34 | 12 | 11 | 11 | 53 | 45 | 8 | 47 | B16:30 | 23/05/21 | R 34 Kickers Würzburg 1 SC Paderborn 1 M16:30 | 16/05/21 | R 33 SC Paderborn 2 Greuther Furth 4 G14:30 | 09/05/21 | R 32 Erzgebirge Aue 3 SC Paderborn 8 G14:00 | 24/04/21 | R 31 SC Paderborn 2 Fortuna Düsseldorf 1 B19:30 | 21/04/21 | R 30 SC Paderborn 2 VfL 1899 Osnabruck 2 B19:30 | 16/04/21 | R 29 E. Braunschweig 0 SC Paderborn 0 |
| 10 | |  Saint Pauli | 34 | 13 | 8 | 13 | 51 | 56 | -5 | 47 | M16:30 | 23/05/21 | R 34 Jahn Regensburg 3 Saint Pauli 0 M16:30 | 16/05/21 | R 33 Saint Pauli 1 Hannover 96 2 M19:30 | 07/05/21 | R 32 Holstein Kiel 4 Saint Pauli 0 G14:30 | 25/04/21 | R 31 Saint Pauli 2 Greuther Furth 1 M19:30 | 21/04/21 | R 30 Fortuna Düsseldorf 2 Saint Pauli 0 G14:00 | 17/04/21 | R 29 Saint Pauli 4 Kickers Würzburg 0 |
| 11 | |  Nürnberg | 34 | 11 | 11 | 12 | 46 | 51 | -5 | 44 | G16:30 | 23/05/21 | R 34 Hannover 96 1 Nürnberg 2 B16:30 | 16/05/21 | R 33 Nürnberg 1 VfL Bochum 1 M21:30 | 10/05/21 | R 32 Hamburger SV 5 Nürnberg 2 B19:30 | 27/04/21 | R 29 Nürnberg 1 Holstein Kiel 1 G14:00 | 24/04/21 | R 31 Nürnberg 3 1. FC Heidenheim 1846 1 G19:30 | 20/04/21 | R 30 Erzgebirge Aue 0 Nürnberg 1 |
| 12 | |  Erzgebirge Aue | 34 | 12 | 8 | 14 | 44 | 53 | -9 | 44 | G16:30 | 23/05/21 | R 34 Erzgebirge Aue 2 VfL 1899 Osnabruck 1 M16:30 | 16/05/21 | R 33 Fortuna Düsseldorf 3 Erzgebirge Aue 0 M14:30 | 09/05/21 | R 32 Erzgebirge Aue 3 SC Paderborn 8 B19:00 | 26/04/21 | R 29 Karlsruher SC 0 Erzgebirge Aue 0 G19:30 | 23/04/21 | R 31 E. Braunschweig 0 Erzgebirge Aue 2 M19:30 | 20/04/21 | R 30 Erzgebirge Aue 0 Nürnberg 1 |
| 13 | |  Hannover 96 | 34 | 12 | 6 | 16 | 53 | 51 | 2 | 42 | M16:30 | 23/05/21 | R 34 Hannover 96 1 Nürnberg 2 G16:30 | 16/05/21 | R 33 Saint Pauli 1 Hannover 96 2 M19:00 | 10/05/21 | R 26 Holstein Kiel 1 Hannover 96 0 M19:30 | 07/05/21 | R 32 Hannover 96 1 SV Darmstadt 1898 2 M14:30 | 25/04/21 | R 31 Sandhausen 4 Hannover 96 2 G19:30 | 21/04/21 | R 30 Hannover 96 3 Jahn Regensburg 1 |
| 14 | |  Jahn Regensburg | 34 | 9 | 11 | 14 | 37 | 50 | -13 | 38 | G16:30 | 23/05/21 | R 34 Jahn Regensburg 3 Saint Pauli 0 M16:30 | 16/05/21 | R 33 Sandhausen 2 Jahn Regensburg 0 M16:30 | 13/05/21 | R 28 Holstein Kiel 3 Jahn Regensburg 2 M14:30 | 09/05/21 | R 32 VfL Bochum 5 Jahn Regensburg 1 B14:30 | 25/04/21 | R 31 Jahn Regensburg 1 Hamburger SV 1 M19:30 | 21/04/21 | R 30 Hannover 96 3 Jahn Regensburg 1 |
| 15 | |  Sandhausen | 34 | 10 | 4 | 20 | 41 | 60 | -19 | 34 | M16:30 | 23/05/21 | R 34 VfL Bochum 3 Sandhausen 1 G16:30 | 16/05/21 | R 33 Sandhausen 2 Jahn Regensburg 0 M14:30 | 09/05/21 | R 32 1. FC Heidenheim 1846 2 Sandhausen 1 M19:30 | 04/05/21 | R 30 Holstein Kiel 2 Sandhausen 0 M19:30 | 28/04/21 | R 28 Greuther Furth 3 Sandhausen 2 G14:30 | 25/04/21 | R 31 Sandhausen 4 Hannover 96 2 |
| 16 | |  VfL 1899 Osnabruck | 34 | 9 | 6 | 19 | 35 | 58 | -23 | 33 | M16:30 | 23/05/21 | R 34 Erzgebirge Aue 2 VfL 1899 Osnabruck 1 G16:30 | 16/05/21 | R 33 VfL 1899 Osnabruck 3 Hamburger SV 2 G14:00 | 08/05/21 | R 32 Kickers Würzburg 1 VfL 1899 Osnabruck 3 M14:00 | 24/04/21 | R 31 VfL 1899 Osnabruck 1 Holstein Kiel 3 B19:30 | 21/04/21 | R 30 SC Paderborn 2 VfL 1899 Osnabruck 2 |
| 17 | |  E. Braunschweig | 34 | 7 | 10 | 17 | 30 | 59 | -29 | 31 | M16:30 | 23/05/21 | R 34 Hamburger SV 4 E. Braunschweig 0 M16:30 | 16/05/21 | R 33 E. Braunschweig 1 Kickers Würzburg 2 B14:00 | 08/05/21 | R 32 Fortuna Düsseldorf 2 E. Braunschweig 2 M19:30 | 23/04/21 | R 31 E. Braunschweig 0 Erzgebirge Aue 2 M19:30 | 20/04/21 | R 30 Greuther Furth 3 E. Braunschweig 0 B19:30 | 16/04/21 | R 29 E. Braunschweig 0 SC Paderborn 0 |
| 18 | |  Kickers Würzburg | 34 | 6 | 7 | 21 | 37 | 69 | -32 | 25 | B16:30 | 23/05/21 | R 34 Kickers Würzburg 1 SC Paderborn 1 G16:30 | 16/05/21 | R 33 E. Braunschweig 1 Kickers Würzburg 2 M14:00 | 08/05/21 | R 32 Kickers Würzburg 1 VfL 1899 Osnabruck 3 B19:30 | 23/04/21 | R 31 Karlsruher SC 2 Kickers Würzburg 2 M19:30 | 20/04/21 | R 30 Kickers Würzburg 1 SV Darmstadt 1898 3 M14:00 | 17/04/21 | R 29 Saint Pauli 4 Kickers Würzburg 0 |
